Russian President Vladimir Putin condemned the killing of Iranian Supreme Leader Ali Khamenei on Sunday, calling the death, which came amid strikes from Israel and the U.S. a ‘cynical violation’ of norms.

Putin made the statement in a letter to Iranian President Masoud Pezeshkian that the Kremlin released to the public in the wake of Khamenei’s death. Saturday’s bold daytime strikes eliminated Khamenei along with several other top Iranian leaders, including the head of the Iranian Revolutionary Guard Corps.

‘Please accept my deep condolences in connection with the murder of the Supreme Leader of the Islamic Republic of Iran, Seyed Ali Khamenei, and members of his family, committed in cynical violation of all norms of human morality and international law,’ Putin wrote.

‘In our country, Ayatollah Khamenei will be remembered as an outstanding statesman who made a huge personal contribution to the development of friendly Russian-Iranian relations and bringing them to the level of a comprehensive strategic partnership,’ Putin continued.

‘I ask you to convey my most sincere sympathy and support to the family and friends of the Supreme Leader, the government and the entire people of Iran,’ he added.

Iranian Ambassador to the United Nations Amir-Saeid Iravani condemned the joint U.S.-Israeli strikes that rained down on his country throughout Saturday during a U.N. Security Council meeting.

Iravani accused the U.S. of undermining its claims of pursuing international stability while attacking a sovereign country for its ‘domestic’ activities.

‘Neither the charter nor international law recognize internal matters of a state as justification for the use of force by other states. The rule of law would be replaced by the rule of force,’ Iravani said.

‘Iran will continue to exercise its right of self-defense decisively and without hesitation until the aggression ceases in full and unequivocal terms.’

On Saturday morning, President Donald Trump ordered the execution of Operation Epic Fury, citing Tehran’s continued efforts to develop a nuclear weapon.

‘It has always been the policy of the United States, in particular my administration, that this terrorist regime can never have a nuclear weapon. I’ll say it again. They can never have a nuclear weapon,’ Trump said in remarks about the attack Saturday.

Trump said the strikes were meant to ‘defend the American people by eliminating imminent threats from the Iranian regime’ and that they had come after Iran had refused to abandon plans to develop nuclear capabilities.

Iravani called the attack a continuation of longstanding U.S. aggression against Iran.

‘Mr. president, this morning the United States regime, jointly and in coordination with the Israeli regime, initiated an unprovoked and premeditated aggression against the Islamic Republic of Iran for the second time in recent months,’ Irvani said, referring to strikes the U.S. carried out against its nuclear enrichment sites last year. ‘The president of the United States and the prime minister of the Israeli regime have openly claimed responsibility for this act of aggression and have explicitly articulated regime change as their objective, an unmistakable admission of their intent to violate Iran’s sovereignty and territorial integrity.’

Fox News’ Leo Briceno and Reuters contributed to this report.

Three U.S. service members were killed and five others were seriously wounded as part of Operation Epic Fury, U.S. Central Command (CENTCOM) said Sunday morning.

In addition, several others sustained minor shrapnel injuries and concussions and are in the process of being returned to duty, CENTCOM announced.

‘The situation is fluid, so out of respect for the families, we will withhold additional information, including the identities of our fallen warriors, until 24 hours after next of kin have been notified,’ CENTCOM said.

This is a developing story. Please check back for updates.

Pope Leo XIV warned Sunday that U.S.-Israel airstrikes on Iran risk plunging the Middle East into an ‘irreparable abyss,’ urging leaders to halt a dangerous spiral of violence.

Speaking at the Angelus, the pontiff expressed ‘deep concern’ over recent developments and called on nations to choose dialogue over war.

‘Stability and peace are not built with mutual threats, nor with weapons, which sow destruction, pain, and death, but only through a reasonable, authentic, and responsible dialogue,’ the pope said, according to Vatican News.

‘Faced with the possibility of a tragedy of enormous proportions,’ he added, ‘I address to the parties involved a heartfelt appeal to assume the moral responsibility to stop the spiral of violence before it becomes an irreparable abyss!’

The pope’s warning came after Israel and the U.S. launched a joint military operation against Iran on Saturday, dubbed ‘Operation Epic Fury.’ The attacks reportedly killed several senior leaders, including Iranian Supreme Leader Ayatollah Ali Khamenei, who ruled the Islamic Republic for more than three decades.

Meanwhile, Iranian airstrikes killed at least eight Israelis on Sunday as Tehran’s latest missile barrage landed miles from Jerusalem.

The pope reinforced his warning in a two-part message posted Sunday morning on X.

‘I am following with deep concern what is happening in the Middle East and in Iran during this tumultuous time,’ he wrote.

‘Stability and peace are not achieved through mutual threats, nor through the use of weapons, which sow destruction, suffering, and death, but only through reasonable, sincere and responsible dialogue.’

In a follow-up post, he warned of ‘the possibility of a tragedy of immense proportions’ and urged all parties involved to ‘assume the moral responsibility of halting the spiral of violence before it becomes an unbridgeable chasm.’

‘May diplomacy regain its proper role, and may the well-being of peoples, who yearn for peaceful existence founded on justice, be upheld. And let us continue to pray for peace,’ he added.

At least nine people are dead and more than two dozen injured after violent clashes outside the U.S. Consulate in Karachi, Pakistan.

Hundreds of protesters stormed the diplomatic compound in a sharp escalation of anti-American demonstrations.

The unrest followed reports that Iran’s supreme leader, Ayatollah Ali Khamenei, was killed in a joint U.S.-Israeli strike, sparking anger among Shiite Muslims in Pakistan.

Witnesses told The Associated Press that many of the protesters were Shiite Muslims who expressed outrage over Khamenei’s reported death and alleged U.S. involvement. Protesters chanted anti-American and anti-Israel slogans, and attempted to breach the consulate’s perimeter.

Security forces deployed police and paramilitary units as clashes intensified outside the compound.

Between 25 and 30 people were wounded in the clashes, according to local officials.

Pakistani authorities tightened security around the consulate and other U.S. diplomatic missions in Lahore, Islamabad and Peshawar amid fears the unrest could spread. The U.S. Embassy in Pakistan issued a security alert urging American citizens to monitor local news, avoid large crowds and remain vigilant.

‘We are monitoring reports of ongoing demonstrations at the U.S. Consulates General in Karachi and Lahore, as well as calls for additional demonstrations at U.S. Embassy Islamabad and Consulate General Peshawar,’ the U.S. Embassy in Islamabad said on X. ‘We advise U.S. citizens in Pakistan to monitor local news and observe good personal security practices, including being aware of your surroundings, avoiding large crowds, and ensuring your STEP registration is up to date.’

The violence comes amid escalating tensions between Iran and the United States over Tehran’s nuclear program, regional influence and support for proxy groups.

Pakistan has seen protests over what demonstrators describe as Western aggression.

The unrest comes as U.S. and Israeli forces continue coordinated strikes targeting Iranian military infrastructure, air defenses and command centers. The Pentagon named the mission Operation Epic Fury, while the Israel Defense Forces called its portion Operation Lion’s Roar. U.S. officials said the strikes aim to degrade Tehran’s military capabilities and neutralize what they describe as imminent threats to the United States and its allies.

American counterterrorism agencies are quietly monitoring suspected sleeper cells on U.S. soil in the wake of joint U.S.–Israel strikes on Iran, stepping up surveillance amid heightened fears of possible retaliation from Iran-linked operatives or sympathizers.

Federal and local law enforcement have also boosted on-the-ground security in major U.S. cities as part of a precautionary posture, even though no specific, credible threats have been publicly identified.

The move comes on the heels of a Saturday morning operation, dubbed Operation Epic Fury, that resulted in the death of Iran’s Supreme Leader Ayatollah Ali Khamenei and several senior Iranian officials in a coordinated U.S.–Israeli military campaign.

Security experts warn that the fallout could extend beyond the Middle East.

‘If ever there’s going to be a Hezbollah cell or a Hamas cell act in the United States in a violent way it’s now,’ Chris Swecker, a former assistant FBI director, told Fox News.

‘Both organizations are Iranian-backed all the way. Both organizations have had a presence in the United States since the 1980s,’ he added.

Swecker said U.S. authorities have long been aware of domestic networks and sympathizers.

‘We know that they have cells here. We also know that there are lone sympathizers, many of whom have come out in these protest groups,’ he added.

He also warned that border security vulnerabilities may have compounded the risk.

‘We just come off four years of open borders, and I have said before that that was an open door for terrorists to terrorist cells and terror sympathizers to infiltrate. Many were already here, but it’s impossible that they would not infiltrate into these particular groups and sort of act as catalysts, as enablers.’

Against that backdrop, the FBI is moving to reinforce its domestic security posture.

FBI Director Kash Patel said Saturday that counterterrorism and intelligence teams are now on high alert amid ongoing U.S. actions involving Iran.

‘Last night, I instructed our Counterterrorism and intelligence teams to be on high alert and mobilize all assisting security assets needed,’ Patel wrote on X.

Patel added that while the U.S. military is handling force protection overseas, the FBI ‘remains at the forefront of deterring attacks here at home’ and will continue working around the clock to protect Americans.

Jason Pack, a retired FBI supervisory special agent and Fox News contributor, said heightened monitoring is routine when U.S. military operations intersect with adversaries that have historically responded through indirect or unconventional means.

‘The intelligence and counterterrorism communities work on this kind of scenario continuously, long before any conflict begins,’ Pack said. ‘When the United States commits to a joint military campaign with Israel, the domestic threat environment doesn’t simply remain static. It could shift, potentially significantly.’

He noted that adversarial actors — including Hezbollah, Hamas’s external networks and Iranian Revolutionary Guard Corps proxies — have historically demonstrated both intent and, in some cases, the capability to retaliate against U.S. military actions.

Meanwhile, Homeland Security Secretary Kristi Noem said she is ‘in direct coordination with our federal intelligence and law enforcement partners as we continue to closely monitor and thwart any potential threats to the homeland.’

The heightened alert comes as parts of the Department of Homeland Security face a partial shutdown, raising additional questions about resources and operational strain at a time when federal agencies are on elevated watch.

While no specific plots have been identified, officials acknowledge the threat environment could shift quickly as tensions overseas evolve and whether that escalation reaches American soil remains to be seen.

Fox News Digital’s Michael Dorgan and Kelley Kramer contributed to this report.